tina huang data scientist
Highly Influential Citations 3. Empirically, the results show that the proposed BERT fine-tuning model with the SRS technique achieves better results. Google Scholar. However, one of my favorites is using supervised learning techniques, such as random forest, SVM, and XGBoost, to discover which features contribute the most to the success of a product. Harris, K. & Nielsen, R. The genetic cost of Neanderthal introgression. This research aims to determine whether a neural response telemetry (NRT) threshold determines the success of surgery. This course is the perfect balance of teaching technical SQL concepts and optimal approaches to solving coding questions on interviews. Details are provided in Data S2.B. F4-statistics further support this view, revealing that Le Piage II is more closely related to the Fournol clusterthan the Vstonice cluster (f4(Mbuti, Le Piage II; Vstonice, Fournol 85)0, Z=6.58). Science 338, 222226 (2012). We visualize the total amount of ROH longer than 4 cM for (a) pre-LGM individuals, (b) Epigravettian- and Magdalenian-associated individuals, (c) individuals carrying high proportions of Sidelkino-related ancestry, and (d) individuals carrying high proportions of Oberkassel-related ancestry. Bilateral trade between China and Russia in 2022 rose 34.3% year-on-year to a record high of 1.28 trillion yuan ($190 billion) in yuan-denominated terms, Chinese customs data showed in early January. 276, 107319 (2022). Int. This is also validated by f4-statistics of the form f4(Mbuti, Zlat k; test1, test2), which are consistent with zero for all other pre-LGM hunter-gatherers (Supplementary Data 2.C), indicating an equidistant relationship of Zlat k to the tested groups. a,b, The ancestries of individuals in the GoyetQ-2 cluster and Iberian hunter-gatherers (HGs) (a) and individuals in the Oberkassel cluster (b) were modelled using qpAdm, with Fournol 85 and Arene Candide 16 representing the Fournol and Villabruna ancestries, respectively. Moreover, previous studies have shown that El Mirn carries a genetic contribution from the Villabruna cluster, which is found in Epigravettian-associated individuals from Italy4,15. Narasimhan, V. M. et al. Sci. 7 and Supplementary Table 3), which coincides roughly with the first appearance of the Oberkassel ancestry in central Europe. Commun. The ROH segments in hunter-gatherer genomes were identified using hapROH101. 5, 820825 (2021). Late Pleistocene human genome suggests a local origin for the first farmers of central Anatolia. Genome Biol. Billed once. The team analysed the genomes of 356 prehistoric hunter gatherers from different archaeological cultures -- including new data sets of 116 individuals from 14 different European and Central Asian countries. The 3 Greatest Moments in science library uga hours History, Addicted to hills science diet adult small bites? In general, the whole point of data warehousing is to get the data from your source to your target. C. Posth and H.Y. This, together with the evidence of Villabruna ancestry in El Mirn 19ka, further suggests that this genetic discontinuity could be the result of palaeogeographic and palaeoecological transformations connected to the LGM32, rather than to the BllingAllerd warming period4,15 (14.712.9ka). Nat. The similarity between Goyet Q116-1 and Goyet Q376-3 and the Fournol cluster is also observed at the mtDNA level, with both groups including individuals who carried mtDNA haplogroup M, which has not been found in European individuals from after the LGM24 (Extended Data Figs. The genomic history of the Iberian Peninsula over the past 8,000 years. Renaud, G., Slon, V., Duggan, A. T. & Kelso, J. Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA. We provide five novel insights into the genomic history of hunter-gatherer populations over a time span of 30,000 years from the Upper Palaeolithic to the Neolithic. With a lot of raw data, you need to put in some work. Showcase your skills and bolster your data science credentials. Skoglund, P. et al. Enjoy maximum flexibility and forget about cramming against the clock. Quat. My experience includes an internship at Goldman Sachs where I did some machine learning work before I took up my current data science job in tech. Ecol. Content on this website is for information only. The latter was created as a support network for women in the industry to discuss, share, and learn from each other.. (black) or 3s.e.m. I help students become independent data scientists who are not just good at data analysis, but are also able to think about their own learning and the world around them. The previous inhabitants may have migrated to the north as their habitat, the 'mammoth' steppe, dwindled," says Johannes Krause, the study's senior author. Tina Huangis a data scientist currently working at a large FAANG enterprise. Sydney, Australia. I love learning new things a. However, the level of genetic continuity between individuals associated with these cultures and the population structure among Epigravettian-associated individuals have not been fully explored. This channel is about data science, learning, and productivity. You have unlimited access to all course materials, downloadable resources, and content updates. Her first stepping stone into data science was being a research assistant in Bioinformatics. Tina Huang: Data science, computer science, and career advice expert. Ringbauer, H., Novembre, J. "At that time, hunter-gatherers with distinct ancestries and appearances started to mix with each other. Internet Explorer). Genetics 203, 881891 (2016). However, the research team found no evidence for this, on the contrary: hunter-gatherer populations associated with the Gravettian culture and living in central and southern Europe are no longer genetically detectable after the LGM. Claim Author Page. The inferred pattern of short ROH (48 cM, visualized in blue) being common is in stark contrast to most later farmer populations, where the majority of individuals have no short ROH whatsoever (see101), and evidences small effective population sizes across West Eurasian hunter-gatherer groups. The sequence alignment/map format and SAMtools. Note: Content may be edited for style and length. The Neolithic transition in the Baltic was not driven by admixture with early European farmers. In this debated framework, Gravettian-associated individuals have been suggested to represent a biologically homogeneous population on the basis of craniometric and genomic data4,22. The LGM could thus have created a corridor south of the Alps for east-to-west human movements that genetically connected hunter-gatherer populations from the Balkans to Iberia, possibly also via dispersals along existing lower-sea-level coasts32. Corporate Financial Managementspring term (BS 2508) Second year of undergraduate. Along with pushing for more accessibility, she also creates content around working in the tech industry, the challenges that come with it, and career advice. Olalde, I. et al. As long asyouget a exam score of 60% or above,youare eligible toreceive aCourse Certificate! Feb 2015 - Jun 20161 year 5 months. Shes currently at Microsoft. (eds. The pre-40kagroup and theFournol and Vstonice clusters are marked as shaded areas in different colours. Le palolithique suprieur en Italie. Skoglund, P. et al. We also do experiments to test out the features we build and see how users respond to them. Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans. This procedure allowed us to manually traverse the ISOGG Y-Haplogroup Tree, checking in a semi-automatic way which positions were covered. Int. This means that you have to set up the database tables to represent the data (which can be done by using the right database design patterns) and then run some SQL queries to extract the data that you need. Max Planck Institute for Evolutionary Anthropology. C. Posth, H.Y., A.G., A.B.R., W.H. Sci. PubMed Green, R. E. et al. Genetic ancestry changes in Stone to Bronze Age transition in the East European plain. However, additional genomes intermediate in time and space are needed to assess whether those two admixture events were independent or part of a common demographic process. Amazing content! Evol. ), no. 537, 2432 (2020). 2011. Evol. First Name Tina #39. Each aDNA library was double indexed60 in 14 parallel 100l reactions using PfuTurbo DNA Polymerase (Agilent). The colours correspond to the grouping of tested populations, dots refer to the f4-values and the dark and light error bars to 1*SE and 3*SE estimated from 5 cM block jackknife, respectively. & Banks, W. E. in Les Socits Gravettiennes du Nord-Ouest Europen: Nouveaux Sites, Nouvelles Donnes, Nouvelles Lectures (eds Touz, O., Goutas, N., Salomon, H. & Noiret, P.) 323266 (Presses Univ. We love meeting interesting people and making new friends. Tina is proud she taught herself SQL from scratch in 11 days to pass her FAANG SQL interview. The purified products were amplified in multiple 100l reactions using Herculase II Fusion DNA Polymerase (Agilent) following the manufacturers specifications with 0.3M of the IS5/IS6 primers. Tina Huang is a statistician who focuses on the statistical modeling and analysis of big data. Proc. This is first detected in an individual from Gross Fredenwalde in northeastern Germany and reaches around 10% in most European hunter-gatherer individuals thereafter (Extended Data Fig. Dots are maximum likelihood estimates and error bars show 95% confidence intervals of the derived allele frequencies (n, the number of individuals in each group, is provided in Supplementary Data 3.G). Hi! Protoc. The Gravettian culture was one of the most widely distributed Upper Palaeolithic cultures across western Eurasia before the LGM19. Grizz, Panda i Lodomir maj rne charaktery, ale pomimo odmiennoci potrafi wspdziaa i wspiera si w kopotach. Originally published at https://365datascience.com on October 1, 2020. 3b). In this period, the Oberkassel-ancestry admixture spread further east, reaching Samara by around 6.5ka, and an increase in Sidelkino ancestry was detected in hunter-gatherers from the Baltic region, which was previously associated with the transition from the Narva culture to the Comb Ceramic culture38,39 (Extended Data Fig. Martiniano, R., De Sanctis, B., Hallast, P. & Durbin, R. Placing ancient DNA sequences into reference phylogenies. In a rotator, samples were digested for at least 16h at 37C, and for pre-treated samples this was followed55 by an additional hour at 56C. Its not just the top 200 that this competition attracts, but anyone interested in data science. Max Planck Institute for Evolutionary Anthropology. Protoc. Here is a sampling of five herbs that have demonstrated potential immune support benefits: 1. Paleogenomic evidence for multi-generational mixing between Neolithic farmers and Mesolithic hunter-gatherers in the Lower Danube Basin. Lifetime access to all course materials and updates. 27, 21852193.e6 (2017). Nature 505, 8791 (2014). Ace the SQL part of any data science job interview and get hired. One of the best-known and most liked personalities in the data community, Tina is a successful YouTuber and works with one of the FAANG companies. a, The genetic ancestry of hunter-gatherers dated between 14ka and 5.2ka modelled using qpAdm, with Oberkassel, Yuzhniy Oleniy Ostrov, Goyet Q-2 and Neolithic farmers from present-day Turkey (Barcn, Mentee and Boncuklu sites) representing Oberkassel (WHG) (blue), Sidelkino (EHG) (red), GoyetQ2 (orange) and Anatolian Neolithic farmer (green) ancestries, respectively. 44, W58W63 (2016). Lazaridis, I. et al. To mark the occasion, rather than doing some data analysis or looking at trends, we wanted to dedicate this bulletin to seven women in tech, data, and science that you should know about. Petr, M., Pbo, S., Kelso, J. She has been working for the data sciences industry since 2014. 4a and Supplementary Data 3.C). Ontario Institute for Cancer Research Toronto, ON. Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. Moreover, the Oberkassel cluster carries both Villabruna ancestry and a contribution from GoyetQ2 ancestry (Supplementary Data 2.J). 4b and Supplementary Data 3.C). Product development is a huge and complex set of processes that rests on many moving parts, lots of hypotheses testing, and ultimately many decisions. of Leiden, 2000). 6 Reasons We Just Cant Stop. Large-scale genomic analysis documents the migrations of Ice Age hunter-gatherers over a period of 30,000 years -- they took shelter in Western Europe but died out on the . My name is Tina Huang and I'm a data scientist at a FAANG company. She graduated with a degree in Computer Science and Applied Math. First, I like it because of how powerful (almost magical) it is in driving decisions. Tina Huang is very empowering, and she knows what she is talking about. Article volume615,pages 117126 (2023)Cite this article. Radiocarbon 55, 163177 (2013). For the placement of individuals onto a Y-chromosomal phylogenetic tree (Extended Data Fig. A deft hand at turning dense and complicated topics into informative and entertaining videos, theres a ton to learn from every single video. The hunter-gatherers were grouped based on their geographic origins and dates (Supplementary Information, section5). ContamLD: estimation of ancient nuclear DNA contamination using breakdown of linkage disequilibrium. Her YouTube channel offers tips on productivity hacks, resume evaluations, data science employment, and more. The y axis shows the average of calibrated radiocarbon dates in thousands of years (kyr) (Supplementary Data 1.A). Second, the ancestry of individuals associated with the Epigravettian culture (Villabruna cluster), which was found to genetically connect European and Near Eastern hunter-gatherers, reached southern Europe well before the transition between the Early and Late Epigravettian4,15 and possibly as early as the GravettianEpigravettian transition. Tina Huang hellotinah@gmail.com | 123-456-7890 | 1 BeepbeepBoop St. Philadelphia, PA 19104 EDUCATION AND HONORS University of Genome Res. A recent bottleneck of Y chromosome diversity coincides with a global change in culture. Dolukhanov, P. in Cultural Transformations and Interactions in Eastern Europe (eds Chapman, J. Okenla is also part of Atomicos Angel Programme 2021, and is an advisory board member for both Coders of Colour and the No.10 Innovation Fellowship. All enrolled students have access to course exams no matter how many lessons they have watched in a course. 116, 105100 (2020). We also genotyped a selection of previously published individuals with the same approach (Supplementary Data 1.G)2,4,30,74,75,76,77,78. In this study, we analyse 356 ancient hunter-gatherer genomes including new genomic data of 116 individuals dated to 355ka alongside a novel contamination-estimation method based on runs of homozygosity. Nature 615, 117126 (2023). Nat. Oxidation of methane into valuable chemicals, such as C 2+ molecules, has been long sought after but the dilemma between high yield and high selectivity of desired products remains. This is . Pseudo-haploid genotypes were called on the targeted SNPs by randomly sampling a single allele at each position, resulting in individuals with 6,600 to 1.07 million SNPs covered on the 1.24-million-SNP panel (Extended Data Table 1 and Supplementary Data 1.A). Follow Author. Curr. It is not intended to provide medical or other professional advice. The version used for this work is archived at https://edmond.mpdl.mpg.de/dataset.xhtml?persistentId=doi:10.17617/3.Y1KJMF. This might also explain the genetic uniformity of the Oberkassel cluster across large parts of western Eurasia but genomic data from between 15 and 14ka is needed to understand the exact dynamics of this turnover. Res. 4 and Supplementary Data 3.C). Dual ancestries and ecologies of the Late Glacial Palaeolithic in Britain. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Vallini, L. et al. PubMed Central "Ice Age survivors." What is surprising is that the Code Cup was so popular that Stanford decided to throw open a Data Science Week in which anyone can submit a code challenge to the top 200 submissions. & Ringbauer, H. hapCon: estimating contamination of ancient genomes by copying from reference haplotypes. Early Alpine occupation backdates westward human migration in Late Glacial Europe. A 5700 year-old human genome and oral microbiome from chewed birch pitch. Yu, H. et al. Mounier, A. et al. A high-coverage genome sequence from an archaic Denisovan individual. Besides El Mirn, who has around 43% Villabruna ancestry, all other Magdalenian-associated individuals have a lower proportion of this component (1929%) and can thus be assigned to the GoyetQ2 cluster (Fig. Since she graduated, shes been working at a company that develops software for the Windows operating system. Much attention has b Fluorescent probes targeting specific organelles are useful tools for understanding their intracellular behaviors.
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